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KMID : 0363220150530010058
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Korean Journal of Dermatology
2015 Volume.53 No. 1 p.58 ~ p.61
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A Case of Unilesional Mycosis Fungoides Treated with Photodynamic Therapy Using Methyl-Aminolevulinate
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Jang Si-Hyeok
Hwang Eun-Jung
Ryu Hyeong-Ho
Cho Kwang-Hyun
Jo Seong-Jin
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Abstract
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Various treatment modalities are available for mycosis fungoides including topical steroids, topical chemotherapy,phototherapy, and spot radiation therapy. However, these modalities do not always result in optimal effects, withefficacy depending on lesion size, number, and location. Photodynamic therapy (PDT) is a recently introducedtherapeutic modality that proved effective in patients with unilesional mycosis fungoides. A 58-year-old womanpresented with a seven-year history of a pruritic erythematous scaly patch on her right thigh. Through skin biopsy,we verified the lesion as mycosis fungoides. The lesion did not respond well to a topical steroid. We opted fortopical PDT with methyl-aminolevulinate (MAL). MAL cream was applied for 4 hours following irradiation with ared light. Four sessions were administered, separated by five weeks. The lesion clinically improved after treatmentwithout severe side effects. PDT using MAL could be considered an effective and tolerable treatment for mycosisfungoides. (Korean J Dermatol 2015;53(1):58∼61)
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KEYWORD
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Methyl-aminolevulinate , Mycosis fungoides , Photodynamic therapy
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